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Thymoma

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Should we treat or not???
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Mechanism of Action
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MDR

1. ADOC
2. PAC

ADOC regimen:
(doxorubicin, cisplatin, vincristine, cyclophosphamide

92% response rate (34 of 37 patients), including complete responses in 43%

PAC regimen:
cisplatin, doxorubicin, cyclophosphamide

50% response rate, including 3 complete responses.

Fornasiero A, Daniele O, Ghiotto C, et al.: Chemotherapy for invasive thymoma: a 13-year experience. Cancer 68(1): 30-33, 1991.

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