AFP >>Produced by: Fetal Yolk Sac; Embryonic carcinoma elements of germ cell tumors. >>Overall, AFP is NOT elevated in pure seminomas. >>Half-life: 5 days B-HCG >>Produced by: Trophoblastic tissues; Syncytiotrophoblastic components of of germ cell tumors. >>Overall, B-HCG is NOT elevated in seminomas. However, about 10% of cases may have low-level elevation of B-HCG. >>beta-hCG is a marker for Gestational Trophoblastic Disease (GTD). However, it is not a reliable marker for Placental Site Trophoblastic Tumors (PST). >>Half-life: 18-24 hours >>There is some cross-reactivity in the radio-immunoassay with luteinizing hormone. Also, hCG can be falsely elevated in patients who use marijuana. CA 19.9 CA 27.29 CA 125 CEA LDH Thyroglobulin
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