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Welcome to Dr. Hamid Sanatinia's Virtual Headquarters
Hypercalcemia of malignancy

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Should we treat or not???
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Mechanism of Action
Dose Modifications (Renal)
Dose Modifications (hepatic)
MDR

Pamidronate
Zoledronic Acid (Zometa)

Pamidronate
Pamidronate 90 mg IV X 1 over 2 hours
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Zoledronic Acid
Zometa 4 mg IV X 1 over 15 minutes

The most reported adverse events are flu-like syndrome, GI reactions, anemia, insomnia, & dyspnea.

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