Taxol+Carboplatin Taxol 175 mg/m2 CIV over 3 h Carboplatin AUC 6.0 Repeat every 3 weeks. Ref. McGuire W.P.: Proc.: ASCO 1993; 12:255 _____________________________________________________ Taxo(3 hr)-Cisplatin Taxol 175 mg/m2 CIV over 3h Day 1. Cisplatin 75 mg/m2 IVPB day 2. Repeat every 3 weeks. _____________________________________________________ Cyclophosphamide-Cisplatin Cyclophosphamide 1000 mg/m2 IVB day 1 Cisplatin 50 mg/m2 IV/2h day 1 Repeat cycle every 28 days. Ref: Decker DG, et al: Obstet Gynecol 60:481 (1982). _____________________________________________________ Taxol(24 hr) Taxol 135 mg/m2 CIV over 24h Repeat every 3 weeks. Ref: Trimble EL, Adams D, Hawkins MJ, et al: J Clin Oncol 11:2405-2410, 1993. _____________________________________________________
Ovarian Cancer Early Stage Risk Assignment: LOW RISK: Stage IA or IB with Grade 1 or 2 HIGH RISK: Stage I with Grade 3 Stage IC with ruptured capsule, ascites, positive peritoneal cytology, or tumor on the surface of ovary Stage II Clear cell histology
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