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Bleeding Patient
Reversing Coumadin
Reversing Heparin
Laboratory Tests in Hematology
Laboratory Tests In Coagulation
Aceruloplasminemia
African Iron Overload
Anemia, microcytic
Antiphospholipid Syndrome
Anemia, Microcytic, real cases
ATIII Deficiency
Atransferrinemia
Aplastic Anemia
B12 deficiency
Basophilia
Coagulation and Cancer
DIC
Essential Thrombocytosis
ENZYME DISORDERS (RBC)
Eosinophilia
Folate Deficiency
Hemoglobinoapthies
Hemoglobin S/C
Hemoglobin S/S
Hemolytic Anemia
Hemochromatosis
Hemophilia
Hemostasis
Heparins
Heparin-induced thrombocytopenia
Hypercoagulable States
Hyper-Ferritinemia
ITP
Iron Chelation
IRON DEFICIENCY
IRON OVERLOAD
IRON STUDIES
Liver and hemostasis
Megaloblastic Anemia
Monocytosis
Myleofibrosis with Myeloid Metaplasia
Neutrophil Structure
vWF
Porphyria
Phorphyrias (AIP)
Phorphyrias (AIP)
Polycythemia Vera
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TTP
Thalassemia
Thrombocytopenia, congenital
Wilson's Disease
Immunological markers
Amicar
Anagrelide
Oral Anticoagulants
Refludan
Hematology Center
IRON OVERLOAD

DDx
Treatment

Differential Diagnosis
1. Homozygous hereditary hemochromatosis
2. Anemia associated with ineffective erythropoiesis (with or without transfusions)
Hereditary & acquired sideroblastic anemia
Thalassemia (major & intermedia)
Dysmyelopoietic refractory anemias
Congenital dyserythropietic anemias (HEMPAS & others)
3. Hereditary hemolytic anemias without transfusion
Hereditary spehrocytosis
Thalassemia minor
4. Intemperate ingestion
Chronic iron tablet ingestion
5. Transfusional iron overload
Severe hemolytic anemias
6. African iron overload

Treatment
1. Phlebotomy
Goal is to make the patient iron deficient. usually we aim for a ferritin at or below 50.

2. Iron-Chelation Therapy
We usually use this method in patients who cannot undergo phlebotomy; for example, in patients who get iron overloaded secondary to frequent blood transfusions.
DEFEROXAMINE 40 mg/kg/day infused subcutaneously.

Facts about IRON:
The obligatory daily loss of iron is 1 mg. This is usually due to the iron lost from desquamated epithelial cells.