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Causes of Megaloblastic Anemia:
B12 deficiency
Folate deficiency
Causes of Macrocytosis:
Megaloblastic Anemia
ETOH
MDS, AA
Hemolytic Anemias (macrocytosis may be the first clue!)
Hypothyroidism
Drugs: AZT, hydroxyurea, myelosuppressives
Artifacts: Cold Agglutinins, etc
Causes of Folate Deficiency:
ETOH
Poor Diet
Sulfasalazine
Pregnancy
Sprue Syndromes
Oral Contraceptive Pills (OCP)
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